NanoImpact Grand Cru, the top-of-the-line in the NanoImpact series,
will lead you to the next stage that you have never experienced.

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NanoImpact Grand Cru is the most unique and highest quality scalp care product
in the NanoImpact series that we have provided since 2006.
NanoImpact Grand Cru contains fifty-nine ingredients suitable for scalp and hair care.
Among them, especially regarding the most featured eleven ingredients selected as
essential ones to be penetrated deep into the pores, including Pidioxidil (Minoxidil derivatives, as moisturizing),
Ceramide NG (as moisturizing), and Tocopheryl Acetate (as product antioxidants),
we encapsulated them in PLGA nanocapsules with our technology and then freeze-dried,
consequently, succeeded in keeping them fresh until
just before using and promoting them to penetrate quickly deep into the pores.
The special scalp care with NanoImpact Grand Cru having
powerful permeability and long-sustainability of PLGA nanocapsules carrying
the above-featured ingredients will maintain
your scalp and hair in a healthier condition than ever.


The product consists of one bottle of
the first agent (lotion) and four vial containers of the second agent (freeze-dried powder).
  • Prepare the mixed lotion

    Fill a certain amount of the first agent (lotion) in a vial container of the second agent (freeze-dried powder), attach a bottle cap, and shake well to dissolve the freeze-dried powder.

    Note: When you use the mixed lotion, shake more than ten times just before using. To use in a fresh state, use up in two weeks.

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  • Apply the mixed lotion directly to the dried scalp

    Since PLGA nanocapsules are weak against heat, refrain from using a hairdryer right after applying the agent.

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  • Massage your scalp

    Massage your scalp gently with your finger cushions using a circular motion. Scalp massage helps to make your blood circulation better and promote hair growth.

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Red Advantage

NanoImpcat Grand Gru

Scalp care product
Freeze-dried powder (0.22g x 4) and Lotion
(e120mL/4 fl.oz.) / for about 2 month use

(Retail price in Japanese market)

Note: Wholesale prices are subject to negotiation.

Moisturizing ingredients






    CAPIXYL (INCI name: APIGENIN, etc.) 

Scientific cosmetics based on the
beauty science research
by Hosokawa Micron

  • Getting Right
    Inside the Skin

    How to deliver beauty ingredients
    right into the depths of the stratum
    corneum? PLGA nanocapsules with
    high permeability and long
    sustainability do just that,
    placing the highest emphasis on
    improving skin quality.

  • 140nm

    No matter how great an ingredient maybe,
    if it can't get inside the skin,it can't carry out its role.
    PLGA nanocapsules have a minuscule size of 140 nanometers.
    This is more than two million times smaller than the size of a pore.
    That's how these nanoparticles deliver beauty ingredients right
    down to the deepest part of the stratum corneum.
    If the particles were any bigger or smaller than this,
    they wouldn't be able to work to the best of their ability.
    The culmination of years of research data is packed into
    these tiny 140-nanometer particles.

  • Long-Lasting

    How to keep delivering
    beauty ingredients
    to your skin in the same condition
    for over 24 hours?
    By the "time-release method"
    of PLGA nanocapsules,
    bringing medical research and
    cosmetics together.

  • How time-release nanoscience works

    The PLGA nanocapsules have a spherical structure like yarn threads entangled.
    The useful ingredients entangled in PLGA nanocapsules are released slowly
    from the spherical structure as if yarns were untied and can stay around
    the stratum corneum for a long time.
    Furthermore, as the PLGA nanocapsules hydrolyzed with the body water are
    promptly discharged out of the body as water and carbon dioxide.
    In other words, only the necessary ingredients keep acting for a long time,
    and PLGA nanocapsules as a career are extremely safe materials for the human body
    and marine environment.